Human Malonyl-CoA decarboxylase, mitochondrial(MLYCD)

Malonyl-CoA decarboxylase (MCD) is a key enzyme in the synthesis of long-chain fatty acids and the regulation of energy metabolism. It catalyzes the decarboxylation of malonyl-CoA, a intermediate in fatty acid synthesis, to produce acetyl-CoA, which can be used in the citric acid cycle for energy production.

MCD is regulated by various factors, including the availability of nutrients, hormones, and other signaling molecules. Dysregulation of MCD has been linked to a number of diseases, including obesity, diabetes, and cardiovascular disease. Inhibitors of MCD have been developed as potential therapeutic agents for these conditions.

MCD is expressed in a variety of tissues, including the liver, skeletal muscle, and adipose tissue. It is a member of the family of enzymes known as acyl-CoA decarboxylases, which also includes 3-ketoacyl-CoA decarboxylase and 3-hydroxybutyryl-CoA decarboxylase.