Specification
| Organism | Zaire ebolavirus (strain Eckron-76) (ZEBOV) (Zaire Ebola virus) |
| Expression Host | Yeast |
| Tag Info | N-terminal 6xHis-tagged |
| Purity | Greater than 85% by SDS-PAGE |
| Uniprot ID | P87670 |
| Gene Names | GP |
| Alternative Names | Cleaved into the following 2 chains: Small/secreted glycoprotein Short name: sGP Delta-peptide |
| Expression Region | Full Length of Mature Protein(33-364aa ) |
| Molecular Weight | 39.3 kDa |
| Protein Sequence | IPLGVIHNSTLQVNDVDKLVCRDKLSSTNQLRSVGLNLEGNGVATDVPSATKRWGFRSGVPPKVVNYEAGEWAENCYNLEIKKPDGSECLPAAPDGIRGFPRCRYVHKVSGTGPCAGDFAFHKEGAFFLYDRLASTVIYRGTTFAEGVVAFLILPQAKKDFFSSHPLREPVNATEDPSSGYYSTTIRYQATGFGTNETEYLFEVDNLTYVQLESRFTPQFLLQLNETIYTSGKRSNTTGKLIWKVNPEIDTTIGEWAFWETKKTSLEKFAVKSCLSQLYQTEPKTSVVRVRRELLPTQGPTQQLKTTKSWLQKIPLQWFKCTVKEGKLQCRI |
| Form | Liquid or Lyophilization |
| Buffer | The default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol if the delivery form is liquid. The lyophilization buffer is Tris/PBS-based buffer, 6% Trehalose, pH 8.0 if the delivery form is lyophilized powder. Please contact us if you have any special requirment. |
| Reconstitution | Please reconstitute protein in deionized sterile water and we recommend that briefly centrifuge thevial prior to opening the vial .We recommend aliquot for long-term storage at -20℃/-80℃. |
Background
| Relevance | sGP seems to possess an anti-inflammatory activity as it can reverse the barrier-decreasing effects of TNF alpha. Might therefore contribute to the lack of inflammatory reaction seen during infection in spite the of extensive necrosis and massive virus production. Does not seem to be involved in activation of primary macrophages. Does not seem to interact specifically with neutrophils Delta-peptide does not seem to be involved in activation of primary macrophages. |
| Involvement in Disease | |
| Subcellular Location | Small/secreted glycoprotein: Secreted, SUBCELLULAR LOCATION: Delta-peptide: Secreted |
| Protein Families | Filoviruses glycoprotein family |
| Tissue Specificity | GP |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |