Specification
| Organism | Poecilobdella viridis (Indian freshwater leech) |
| Expression Host | Yeast |
| Tag Info | Tag-Free |
| Purity | >96% as determined by SDS-PAGE and HPLC. |
| Uniprot ID | P84590 |
| Uniprot Entry Name | HIRUD_POEVI |
| Gene Names | N/A |
| Alternative Names | |
| Expression Region | Full Length (1-63aa) |
| Molecular Weight | 6.7 kDa |
| Endotoxin | Less than 1.0 EU/µg as determined by LAL method. |
| Sequence | VVYTDCTESG QNLCLCEGSN VCGQGNKCIL GSDGEKNQCV TGEGTPGPQS HNDGDFEEPE EYL |
| Product Form | Lyophilized powder (Lyophilized from a 0.2 μm filtered 20 mM PBS, pH 7.0, containing 2 % mannitol) |
| Reconstitution | Please reconstitute protein in deionized sterile water and we recommend that briefly centrifuge thevial prior to opening the vial .We recommend aliquot for long-term storage at -20℃/-80℃. |
Background
| Relevance | Hirudin is a potent thrombin-specific protease inhibitor. It forms a stable non-covalent complex with alpha-thrombin, thereby abolishing its ability to cleave fibrinogen. |
| Function | Hirudin is a potent thrombin-specific protease inhibitor. It forms a stable non-covalent complex with alpha-thrombin, thereby abolishing its ability to cleave fibrinogen. |
| Involvement in disease | |
| Subcellular Location | Secreted |
| Protein Families | Protease inhibitor I14 (hirudin) family |
| Tissue Specificity | |
| Pathway |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |