Specification
| Organism | Pandinus imperator (Emperor scorpion) |
| Expression Host | Yeast |
| Tag Info | N-terminal 6xHis-tagged |
| Purity | Greater than 85% by SDS-PAGE |
| Uniprot ID | P83240 |
| Gene Names | N/A |
| Alternative Names | Non-disulfide-bridged peptide 3.1 Short name: NDBP-3.1 Non-disulfide-bridged peptide 4.1 Short name: NDBP-4.1 |
| Expression Region | Full Length(1-24aa ) |
| Molecular Weight | 4.6 kDa |
| Protein Sequence | FWGALAKGALKLIPSLFSSFSKKD |
| Form | Liquid or Lyophilization |
| Buffer | The default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol if the delivery form is liquid. The lyophilization buffer is Tris/PBS-based buffer, 6% Trehalose, pH 8.0 if the delivery form is lyophilized powder. Please contact us if you have any special requirment. |
| Reconstitution | Please reconstitute protein in deionized sterile water and we recommend that briefly centrifuge thevial prior to opening the vial .We recommend aliquot for long-term storage at -20℃/-80℃. |
Background
| Relevance | Disrupts cell membranes through formation of pores. Has strong antimicrobial activity against Gram-positive bacteria B.subtilis, S.epidermidis, E.faecalis and S.aureus. Is less active against Gram-negative bacteria P.aeruginosa and E.coli. Also increases efficacy of antibiotics (ampicillin, chloramphenicol, streptomycin, kanamycin, novobiocin) when tested against E.coli, probably by facilitating their incorporation into the bacteria. Possesses antifungal activity against C.albicans and hemolytic activity against human, sheep and pig erythrocytes. |
| Involvement in Disease | |
| Subcellular Location | Secreted, Target cell membrane |
| Protein Families | Non-disulfide-bridged peptide (NDBP) superfamily, Medium-length antimicrobial peptide (group 3) family |
| Tissue Specificity | N/A |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |