Specification
| Organism | Mus musculus (Mouse) |
| Expression Host | E.Coli |
| Tag Info | Tag-Free |
| Purity | >97% as determined by SDS-PAGE and HPLC. |
| Uniprot ID | P47993 |
| Uniprot Entry Name | XCL1_MOUSE |
| Gene Names | Xcl1,Lptn,Ltn,Scyc1 |
| Alternative Names | C motif chemokine 1, Lymphotaxin, Small-inducible cytokine C1 |
| Expression Region | Full Length of Mature Protein (22-114aa) |
| Molecular Weight | 10.1 kDa |
| Endotoxin | Less than 1.0 EU/µg as determined by LAL method. |
| Sequence | VGTEVLEESS CVNLQTQRLP VQKIKTYIIW EGAMRAVIFV TKRGLKICAD PEAKWVKAAI KTVDGRASTR KNMAETVPTG AQRSTSTAIT LTG |
| Product Form | Lyophilized powder (Lyophilized from a 0.2 µm filtered PBS, pH 7.4) |
| Reconstitution | Please reconstitute protein in deionized sterile water and we recommend that briefly centrifuge thevial prior to opening the vial .We recommend aliquot for long-term storage at -20℃/-80℃. |
Background
| Relevance | Chemotactic activity for lymphocytes but not for monocytes or neutrophils. |
| Function | Chemotactic activity for lymphocytes but not for monocytes or neutrophils. In thymus, mediates medullary accumulation of thymic dendritic cells and contributes to regulatoy T cell development, playing a role in self-tolerance establishment. |
| Involvement in disease | |
| Subcellular Location | Secreted |
| Protein Families | Intercrine gamma family |
| Tissue Specificity | Expressed in activated CD8(+) T cells. In the thymus, expressed by medullary thymic epithelial cells. |
| Pathway |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |