Specification
| Organism | Mus musculus (Mouse) |
| Expression Host | Yeast |
| Tag Info | N-terminal 6xHis-tagged |
| Purity | Greater than 85% by SDS-PAGE |
| Uniprot ID | O09051 |
| Gene Names | Guca2b |
| Alternative Names | Guca2b; Guanylate cyclase activator 2B [Cleaved into: Uroguanylin; UGN)] |
| Expression Region | Full Length of Mature Protein(22-106aa ) |
| Molecular Weight | 11.4 kDa |
| Protein Sequence | VYIKYHGFQVQLESVKKLNELEEKEMSNPQPRRSGLLPAVCHNPALPLDLQPVCASQEAASTFKALRTIATDECELCINVACTGC |
| Form | Liquid or Lyophilization |
| Buffer | The default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol if the delivery form is liquid. The lyophilization buffer is Tris/PBS-based buffer, 6% Trehalose, pH 8.0 if the delivery form is lyophilized powder. Please contact us if you have any special requirment. |
| Reconstitution | Please reconstitute protein in deionized sterile water and we recommend that briefly centrifuge thevial prior to opening the vial .We recommend aliquot for long-term storage at -20℃/-80℃. |
Background
| Relevance | Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. May be a potent physiological regulator of intestinal fluid and electrolyte transport. May be an autocrine/paracrine regulator of intestinal salt and water transport . |
| Involvement in Disease | |
| Subcellular Location | Secreted |
| Protein Families | Guanylin family |
| Tissue Specificity | Guca2b |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |