Specification
| Organism | Mus musculus (Mouse) |
| Expression Host | E.Coli |
| Tag Info | Tag-Free |
| Purity | >98% as determined by SDS-PAGE and HPLC. |
| Uniprot ID | P10855 |
| Uniprot Entry Name | CCL3_MOUSE |
| Gene Names | Ccl3,Mip1a,Scya3 |
| Alternative Names | Heparin-binding chemotaxis protein, Macrophage inflammatory protein 1-alpha, MIP-1-alpha, SIS-alpha, Small-inducible cytokine A3 |
| Expression Region | Full Length of Mature Protein (24-92aa) |
| Molecular Weight | 7.9 kDa |
| Endotoxin | Less than 1.0 EU/µg as determined by LAL method. |
| Sequence | APYGADTPTA CCFSYSRKIP RQFIVDYFET SSLCSQPGVI FLTKRNRQIC ADSKETWVQE YITDLELNA |
| Product Form | Lyophilized powder (Lyophilized from a 0.2 μm filtered concentrated solution in 30 % Acetonitrile and 0.1 % TFA) |
| Reconstitution | Please reconstitute protein in deionized sterile water and we recommend that briefly centrifuge thevial prior to opening the vial .We recommend aliquot for long-term storage at -20℃/-80℃. |
Background
| Relevance | Monokine with inflammatory, pyrogenic and chemokinetic properties. Has a potent chemotactic activity for eosinophils. Binding to a high-affinity receptor activates calcium release in neutrophils. |
| Function | Monokine with inflammatory, pyrogenic and chemokinetic properties. Has a potent chemotactic activity for eosinophils. Binding to a high-affinity receptor activates calcium release in neutrophils. |
| Involvement in disease | |
| Subcellular Location | Secreted |
| Protein Families | Intercrine beta (chemokine CC) family |
| Tissue Specificity | Expressed in lung, spleen, and pancreas. |
| Pathway |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |