Specification
| Organism | Klebsiella pneumoniae |
| Expression Host | E.coli |
| Tag Info | N-terminal 6xHis-SUMO-tagged |
| Purity | Greater than 85% by SDS-PAGE |
| Uniprot ID | C7C422 |
| Gene Names | blaNDM-1 |
| Alternative Names | Metallo-beta-lactamase NDM-1 |
| Expression Region | Full Length of Mature Protein(29-270aa ) |
| Molecular Weight | 41.6 kDa |
| Protein Sequence | GEIRPTIGQQMETGDQRFGDLVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLVVDTAWTDDQTAQILNWIKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPQEGMVAAQHSLTFAANGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIKDSKAKSLGNLGDADTEHYAASARAFGAAFPKASMIVMSHSAPDSRAAITHTARMADKLR |
| Form | Liquid or Lyophilization |
| Buffer | The default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol if the delivery form is liquid. The lyophilization buffer is Tris/PBS-based buffer, 6% Trehalose, pH 8.0 if the delivery form is lyophilized powder. Please contact us if you have any special requirment. |
| Reconstitution | Please reconstitute protein in deionized sterile water and we recommend that briefly centrifuge thevial prior to opening the vial .We recommend aliquot for long-term storage at -20℃/-80℃. |
Background
| Relevance | Confers resistance to many beta-lactam antibiotics, including some carbapens. Does not confer resistance to the polymixin colistin or the fluoroquinolone ciprofloxacin. |
| Involvement in Disease | |
| Subcellular Location | Periplasm |
| Protein Families | Metallo-beta-lactamase superfamily, Class-B beta-lactamase family |
| Tissue Specificity | blaNDM-1 |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |