Specification
| Organism | Homo sapiens (Human) |
| Expression Host | E.coli |
| Protein Tag | N-terminal 6xHis-tagged |
| Purity | Greater than 85% as determined by SDS-PAGE. |
| Endotoxin Level | Not test. |
| Biological Activity | |
| Uniprot ID | Q9Y2Y4 |
| Gene Names | ZBTB32 |
| Alternative Names | (FANCC-interacting protein)(Fanconi anemia zinc finger protein)(Testis zinc finger protein)(Zinc finger protein 538) |
| Expression Region | 1-294aa |
| Product Form | Liquid or Lyophilized powder |
| Buffer | The default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol if the delivery form is liquid. The lyophilization buffer is Tris/PBS-based buffer, 6% Trehalose, pH 8.72 if the delivery form is lyophilized powder. Please contact us if you have any special requirment. |
| Reconstitution | Please reconstitute protein in deionized sterile water and we recommend that briefly centrifuge thevial prior to opening the vial .We recommend aliquot for long-term storage at -20℃/-164℃. |
| Protein Length | Partial |
| Molecular Weight | 36.5 kDa |
| Protein Sequence | MSLPPIRLPSPYGSDRLVQLAARLRPALCDTLITVGSQEFPAHSLVLAGVSQQLGRRGQWALGEGISPSTFAQLLNFVYGESVELQPGELRPLQEAARALGVQSLEEACWRARGDRAKKPDPGLKKHQEEPEKPSRNPERELGDPGEKQKPEQVSRTGGREQEMLHKHSPPRGRPEMAGATQEAQQEQTRSKEKRLQAPVGQRGADGKHGVLTWLRENPGGSEESLRKLPGPLPPAGSLQTSVTPRPSWAEAPWLVGGQPALWSILLMPPRYGIPFYHSTPTTGAWQEVWREQR |
Background
| Research Areas | Epigenetics and Nuclear Signaling |
| Relevance | DNA-binding protein that binds to the to a 5'-TGTACAGTGT-3' core sequence. May function as a transcriptional transactivator and transcriptional repressor. Probably exerts its repressor effect by preventing GATA3 from binding to DNA. May play a role in regulating the differentiation and activation of helper T-cells. |
| Function | |
| Reference | "Insights into strand exchange in BTB domain dimers from the crystal structures of FAZF and Miz1." Stogios P.J., Cuesta-Seijo J.A., Chen L., Pomroy N.C., Prive G.G. J. Mol. Biol. 400:983-997(2010) |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |