Specification
| Organism | Homo sapiens (Human) |
| Expression Host | E.Coli |
| Tag Info | Tag-Free |
| Purity | >95% as determined by SDS-PAGE. |
| Uniprot ID | Q96RJ3 |
| Uniprot Entry Name | TR13C_HUMAN |
| Gene Names | TNFRSF13C,BAFFR,BR3 |
| Alternative Names | B-cell-activating factor receptor, BAFF-R, BLyS receptor 3, CD antigen CD268, |
| Expression Region | Partial (1-76aa) |
| Molecular Weight | 7.8 kDa |
| Endotoxin | Less than 1.0 EU/µg as determined by LAL method. |
| Sequence | MRRGPRSLRG RDAPAPTPCV PAECFDLLVR HCVACGLLRT PRPKPAGASS PAPRTALQPQ ESVGAGAGEA ALPLPG |
| Product Form | Lyophilized powder (Lyophilized from a 0.2 µm filtered 20 mM PB, pH 8.0, 500 mM NaCl) |
| Reconstitution | Please reconstitute protein in deionized sterile water and we recommend that briefly centrifuge thevial prior to opening the vial .We recommend aliquot for long-term storage at -20℃/-80℃. |
Background
| Relevance | B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response. {ECO:0000269|PubMed:11591325, ECO:0000269|PubMed:12387744}. |
| Function | B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response. |
| Involvement in disease | Immunodeficiency, common variable, 4 (CVID4) |
| Subcellular Location | Membrane, Single-pass type III membrane protein |
| Protein Families | |
| Tissue Specificity | Highly expressed in spleen and lymph node, and in resting B-cells. Detected at lower levels in activated B-cells, resting CD4+ T-cells, in thymus and peripheral blood leukocytes. |
| Pathway | NF-kappaBsignalingpathway |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |