Specification
| Description | Recombinant protein from the full-length sequence of Homo sapiens tribbles pseudokinase 2 (TRIB2), transcript variant 1 (NM_021643). |
| Organism | Homo sapiens (Human) |
| Expression Host | Human Cells |
| Tag Info | His or DYKDDDDK. Please contact us if you need further information or require specific designed tag. |
| Purity | Greater than 90% by SDS-PAGE gel |
| Uniprot ID | Q92519 |
| Entry Name | TRIB2_HUMAN |
| Gene Names | TRIB2 TRB2 |
| Alternative Gene Names | TRB2 |
| Alternative Protein Names | Tribbles homolog 2 (TRB-2) |
| Application | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only! |
| Buffer | Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives |
| Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
| Length | 343 |
| Molecular Weight(Da) | 38801 |
| Protein Sequence | (The sequence of expressed protein may have some variation from the sequence shown below. Please contact us for the exact sequence.) MNIHRSTPITIARYGRSRNKTQDFEELSSIRSAEPSQSFSPNLGSPSPPETPNLSHCVSCIGKYLLLEPLEGDHVFRAVHLHSGEELVCKVFDISCYQESLAPCFCLSAHSNINQITEIILGETKAYVFFERSYGDMHSFVRTCKKLREEEAARLFYQIASAVAHCHDGGLVLRDLKLRKFIFKDEERTRVKLESLEDAYILRGDDDSLSDKHGCPAYVSPEILNTSGSYSGKAADVWSLGVMLYTMLVGRYPFHDIEPSSLFSKIRRGQFNIPETLSPKAKCLIRSILRREPSERLTSQEILDHPWFSTDFSVSNSAYGAKEVSDQLVPDVNMEENLDPFFN |
Background
| Function | FUNCTION: Interacts with MAPK kinases and regulates activation of MAP kinases. Does not display kinase activity (By similarity). {ECO:0000250|UniProtKB:Q28283, ECO:0000250|UniProtKB:Q96RU8}. |
| Pathway | |
| Protein Families | Protein kinase superfamily, CAMK Ser/Thr protein kinase family, Tribbles subfamily |
| Tissue Specificity | Highly expressed in peripheral blood leukocytes. {ECO:0000269|PubMed:15299019}. |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |