Specification
| Organism | Homo sapiens (Human) |
| Expression Host | E.Coli |
| Tag Info | Tag-Free |
| Purity | >97% as determined by SDS-PAGE and HPLC. |
| Uniprot ID | Q07654 |
| Uniprot Entry Name | TFF3_HUMAN |
| Gene Names | TFF3,ITF,TFI |
| Alternative Names | Intestinal trefoil factor, Polypeptide P1.B, hP1.B |
| Expression Region | Full Length of Mature Protein (22-80aa) |
| Molecular Weight | 6.6 kDa |
| Endotoxin | Less than 1.0 EU/µg as determined by LAL method. |
| Sequence | EEYVGLSANQ CAVPAKDRVD CGYPHVTPKE CNNRGCCFDS RIPGVPWCFK PLQEAECTF |
| Product Form | Lyophilized powder (Lyophilized from a 0.2 µm filtered 20 mM PB, pH 7.4, 150mM NaCl) |
| Reconstitution | Please reconstitute protein in deionized sterile water and we recommend that briefly centrifuge thevial prior to opening the vial .We recommend aliquot for long-term storage at -20℃/-80℃. |
Background
| Relevance | Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen). {ECO:0000269|PubMed:11694446}. |
| Function | Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen). |
| Involvement in disease | |
| Subcellular Location | Secreted, extracellular space, extracellular matrix, Cytoplasm |
| Protein Families | |
| Tissue Specificity | Expressed in goblet cells of the intestines and colon (at protein level). Expressed by goblet cells of small and large intestinal epithelia and also by the uterus. Also expressed in the hypothalamus where it is detected in paraventricular, periventricular and supraoptic nuclei (at protein level). |
| Pathway |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |