Specification
| Organism | Homo sapiens (Human) |
| Expression Host | E.coli |
| Tag Info | N-terminal GST-tagged |
| Purity | Greater than 85% by SDS-PAGE |
| Uniprot ID | Q14232 |
| Gene Names | EIF2B1 |
| Alternative Names | eIF-2B GDP-GTP exchange factor subunit alpha |
| Expression Region | Full Length(1-305aa ) |
| Molecular Weight | 60.7 kDa |
| Protein Sequence | MDDKELIEYFKSQMKEDPDMASAVAAIRTLLEFLKRDKGETIQGLRANLTSAIETLCGVDSSVAVSSGGELFLRFISLASLEYSDYSKCKKIMIERGELFLRRISLSRNKIADLCHTFIKDGATILTHAYSRVVLRVLEAAVAAKKRFSVYVTESQPDLSGKKMAKALCHLNVPVTVVLDAAVGYIMEKADLVIVGAEGVVENGGIINKIGTNQMAVCAKAQNKPFYVVAESFKFVRLFPLNQQDVPDKFKYKADTLKVAQTGQDLKEEHPWVDYTAPSLITLLFTDLGVLTPSAVSDELIKLYL |
| Form | Liquid or Lyophilization |
| Buffer | The default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol if the delivery form is liquid. The lyophilization buffer is Tris/PBS-based buffer, 6% Trehalose, pH 8.0 if the delivery form is lyophilized powder. Please contact us if you have any special requirment. |
| Reconstitution | Please reconstitute protein in deionized sterile water and we recommend that briefly centrifuge thevial prior to opening the vial .We recommend aliquot for long-term storage at -20℃/-80℃. |
Background
| Relevance | Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. |
| Involvement in Disease | Leukodystrophy with vanishing white matter (VWM) |
| Subcellular Location | |
| Protein Families | EIF-2B alpha/beta/delta subunits family |
| Tissue Specificity | EIF2B1 |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |