Specification
| Organism | Homo sapiens (Human) |
| Expression Host | E.Coli |
| Tag Info | Tag-Free |
| Purity | >97% as determined by SDS-PAGE and HPLC. |
| Uniprot ID | P62328 |
| Uniprot Entry Name | TYB4_HUMAN |
| Gene Names | TMSB4X,TB4X,THYB4,TMSB4 |
| Alternative Names | T beta-4, |
| Expression Region | Full Length of Mature Protein (2-44aa) |
| Molecular Weight | 4.9 kDa |
| Endotoxin | Less than 1.0 EU/µg as determined by LAL method. |
| Sequence | SDKPDMAEIE KFDKSKLKKT ETQEKNPLPS KETIEQEKQA GES |
| Product Form | Lyophilized powder (Lyophilized from a 0.2 µm filtered concentrated solution in 20 mM PB, pH 7.4.) |
| Reconstitution | Please reconstitute protein in deionized sterile water and we recommend that briefly centrifuge thevial prior to opening the vial .We recommend aliquot for long-term storage at -20℃/-80℃. |
Background
| Relevance | Plays an important role in the organization of the cytoskeleton (By similarity). Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. {ECO:0000250}.; Seraspenide inhibits the entry of hematopoietic pluripotent stem cells into the S-phase. {ECO:0000250}. |
| Function | Plays an important role in the organization of the cytoskeleton (By similarity). Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. |
| Involvement in disease | |
| Subcellular Location | Cytoplasm, cytoskeleton |
| Protein Families | Thymosin beta family |
| Tissue Specificity | Expressed in several hemopoietic cell lines and lymphoid malignant cells. Decreased levels in myeloma cells. |
| Pathway | Regulationofactincytoskeleton |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |