Specification
| Description | Recombinant protein from the full-length sequence of homo sapiens serine/threonine kinase 19 (STK19), transcript variant 1 (NM_004197). |
| Organism | Homo sapiens (Human) |
| Expression Host | Human Cells |
| Tag Info | His or DYKDDDDK. Please contact us if you need further information or require specific designed tag. |
| Purity | Greater than 90% by SDS-PAGE gel |
| Uniprot ID | P49842 |
| Entry Name | STK19_HUMAN |
| Gene Names | STK19 G11 RP1 |
| Alternative Gene Names | G11 RP1 |
| Alternative Protein Names | Serine/threonine-protein kinase 19 (EC 2.7.11.1) (Protein G11) (Protein RP1) |
| Application | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only! |
| Buffer | Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives |
| Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
| Length | 368 |
| Molecular Weight(Da) | 40916 |
| Protein Sequence | (The sequence of expressed protein may have some variation from the sequence shown below. Please contact us for the exact sequence.) MQKWFSAFDDAIIQRQWRANPSRGGGGVSFTKEVDTNVATGAPPRRQRVPGRACPWREPIRGRRGARPGGGDAGGTPGETVRHCSAPEDPIFRFSSLHSYPFPGTIKSRDMSWKRHHLIPETFGVKRRRKRGPVESDPLRGEPGSARAAVSELMQLFPRGLFEDALPPIVLRSQVYSLVPDRTVADRQLKELQEQGEIRIVQLGFDLDAHGIIFTEDYRTRVCDCVLKACDGRPYAGAVQKFLASVLPACGDLSFQQDQMTQTFGFRDSEITHLVNAGVLTVRDAGSWWLAVPGAGRFIKYFVKGRQAVLSMVRKAKYRELLLSELLGRRAPVVVRLGLTYHVHDLIGAQLVDCISTTSGTLLRLPET |
Background
| Function | FUNCTION: Serine/threonine-protein kinase that acts as a key regulator of NRAS signaling by mediating phosphorylation of NRAS at 'Ser-89', thereby enhancing NRAS-binding to its downstream effectors. {ECO:0000269|PubMed:30712867}. |
| Pathway | |
| Protein Families | STK19 family |
| Tissue Specificity | Monocytes, hepatocytes, epithelial cells, T- and B-lymphocytes. {ECO:0000269|PubMed:8012361}. |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |