Specification
| Description | Recombinant protein from the full-length sequence of homo sapiens steroidogenic acute regulatory protein (STAR) (NM_000349). |
| Organism | Homo sapiens (Human) |
| Expression Host | Human Cells |
| Tag Info | His or DYKDDDDK. Please contact us if you need further information or require specific designed tag. |
| Purity | Greater than 90% by SDS-PAGE gel |
| Uniprot ID | P49675 |
| Entry Name | STAR_HUMAN |
| Gene Names | STAR STARD1 |
| Alternative Gene Names | STARD1 |
| Alternative Protein Names | Steroidogenic acute regulatory protein, mitochondrial (StAR) (START domain-containing protein 1) (StARD1) |
| Application | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only! |
| Buffer | Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives |
| Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
| Length | 285 |
| Molecular Weight(Da) | 31914 |
| Protein Sequence | (The sequence of expressed protein may have some variation from the sequence shown below. Please contact us for the exact sequence.) MLLATFKLCAGSSYRHMRNMKGLRQQAVMAISQELNRRALGGPTPSTWINQVRRRSSLLGSRLEETLYSDQELAYLQQGEEAMQKALGILSNQEGWKKESQQDNGDKVMSKVVPDVGKVFRLEVVVDQPMERLYEELVERMEAMGEWNPNVKEIKVLQKIGKDTFITHELAAEAAGNLVGPRDFVSVRCAKRRGSTCVLAGMATDFGNMPEQKGVIRAEHGPTCMVLHPLAGSPSKTKLTWLLSIDLKGWLPKSIINQVLSQTQVDFANHLRKRLESHPASEARC |
Background
| Function | FUNCTION: Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. {ECO:0000269|PubMed:7761400, ECO:0000269|PubMed:7892608, ECO:0000269|PubMed:8948562}. |
| Pathway | Steroid metabolism; cholesterol metabolism. |
| Protein Families | |
| Tissue Specificity | Expressed in gonads, adrenal cortex and kidney. |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |