Specification
| Organism | Homo sapiens (Human) |
| Expression Host | E.coli |
| Tag Info | N-terminal 10xHis-tagged and C-terminal Myc-tagged |
| Purity | Greater than 85% by SDS-PAGE |
| Uniprot ID | Q8WXA9 |
| Gene Names | SREK1 |
| Alternative Names | Serine/arginine-rich-splicing regulatory protein 86 (SRrp86) (Splicing factor, arginine/serine-rich 12) (Splicing regulatory protein 508 ) (SRrp508) |
| Expression Region | Partial(421-508aa ) |
| Molecular Weight | 17.3 kDa |
| Protein Sequence | KERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKIQHNGNCQLNEENLSTKTEAV |
| Form | Liquid or Lyophilization |
| Buffer | The default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol if the delivery form is liquid. The lyophilization buffer is Tris/PBS-based buffer, 6% Trehalose, pH 8.0 if the delivery form is lyophilized powder. Please contact us if you have any special requirment. |
| Reconstitution | Please reconstitute protein in deionized sterile water and we recommend that briefly centrifuge thevial prior to opening the vial .We recommend aliquot for long-term storage at -20℃/-80℃. |
Background
| Relevance | Participates in the regulation of alternative splicing by modulating the activity of other splice facors. Inhibits the splicing activity of SFRS1, SFRS2 and SFRS6. Augments the splicing activity of SFRS3 |
| Involvement in Disease | |
| Subcellular Location | Nucleus |
| Protein Families | Splicing factor SR family |
| Tissue Specificity | SREK1 |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |