Specification
| Description | Recombinant protein from the full-length sequence of Homo sapiens serpin family B member 10 (SERPINB10) (NM_005024). |
| Organism | Homo sapiens (Human) |
| Expression Host | Human Cells |
| Tag Info | His or DYKDDDDK. Please contact us if you need further information or require specific designed tag. |
| Purity | Greater than 90% by SDS-PAGE gel |
| Uniprot ID | P48595 |
| Entry Name | SPB10_HUMAN |
| Gene Names | SERPINB10 PI10 |
| Alternative Gene Names | PI10 |
| Alternative Protein Names | Serpin B10 (Bomapin) (Peptidase inhibitor 10) (PI-10) |
| Application | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only! |
| Buffer | Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives |
| Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
| Length | 397 |
| Molecular Weight(Da) | 45403 |
| Protein Sequence | (The sequence of expressed protein may have some variation from the sequence shown below. Please contact us for the exact sequence.) MDSLATSINQFALELSKKLAESAQGKNIFFSSWSISTSLTIVYLGAKGTTAAQMAQVLQFNRDQGVKCDPESEKKRKMEFNLSNSEEIHSDFQTLISEILKPNDDYLLKTANAIYGEKTYAFHNKYLEDMKTYFGAEPQPVNFVEASDQIRKDINSWVERQTEGKIQNLLPDDSVDSTTRMILVNALYFKGIWEHQFLVQNTTEKPFRINETTSKPVQMMFMKKKLHIFHIEKPKAVGLQLYYKSRDLSLLILLPEDINGLEQLEKAITYEKLNEWTSADMMELYEVQLHLPKFKLEDSYDLKSTLSSMGMSDAFSQSKADFSGMSSARNLFLSNVFHKAFVEINEQGTEAAAGSGSEIDIRIRVPSIEFNANHPFLFFIRHNKTNTILFYGRLCSP |
Background
| Function | FUNCTION: Protease inhibitor that may play a role in the regulation of protease activities during hematopoiesis and apoptosis induced by TNF. May regulate protease activities in the cytoplasm and in the nucleus. {ECO:0000269|PubMed:10871600, ECO:0000269|PubMed:7592909}. |
| Pathway | |
| Protein Families | Serpin family, Ov-serpin subfamily |
| Tissue Specificity | Expressed specifically in myeloid cells and the bone marrow. {ECO:0000269|PubMed:20433722, ECO:0000269|PubMed:7592909}. |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |