Specification
| Description | Recombinant protein from the full-length sequence of Homo sapiens secretion associated Ras related GTPase 1B (SAR1B), transcript variant 2 (NM_016103). |
| Organism | Homo sapiens (Human) |
| Expression Host | Human Cells |
| Tag Info | His or DYKDDDDK. Please contact us if you need further information or require specific designed tag. |
| Purity | Greater than 90% by SDS-PAGE gel |
| Uniprot ID | Q9Y6B6 |
| Entry Name | SAR1B_HUMAN |
| Gene Names | SAR1B SARA2 SARB |
| Alternative Gene Names | SARA2 SARB |
| Alternative Protein Names | GTP-binding protein SAR1b (GTP-binding protein B) (GTBPB) |
| Application | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only! |
| Buffer | Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives |
| Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
| Length | 198 |
| Molecular Weight(Da) | 22410 |
| Protein Sequence | (The sequence of expressed protein may have some variation from the sequence shown below. Please contact us for the exact sequence.) MSFIFDWIYSGFSSVLQFLGLYKKTGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPTSEELTIAGMTFTTFDLGGHVQARRVWKNYLPAINGIVFLVDCADHERLLESKEELDSLMTDETIANVPILILGNKIDRPEAISEERLREMFGLYGQTTGKGSISLKELNARPLEVFMCSVLKRQGYGEGFRWMAQYID |
Background
| Function | FUNCTION: GTP-binding protein involved in transport from the endoplasmic reticulum to the Golgi apparatus (By similarity). Activated by the guanine nucleotide exchange factor PREB (By similarity). Involved in the selection of the protein cargo and the assembly of the COPII coat complex (By similarity). Synergizes with the cargo receptor SURF4 to mediate the export of lipoproteins from the endoplasmic reticulum, thereby regulating lipoprotein delivery and the maintenance of lipid homeostasis (PubMed:33186557). {ECO:0000250|UniProtKB:Q9QVY3, ECO:0000269|PubMed:33186557}. |
| Pathway | |
| Protein Families | Small GTPase superfamily, SAR1 family |
| Tissue Specificity | Expressed in many tissues including small intestine, liver, muscle and brain. {ECO:0000269|PubMed:12692552}. |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |