Specification
| Description | Recombinant protein from the full-length sequence of Homo sapiens RNA transcription, translation and transport factor (RTRAF) (NM_016039). |
| Organism | Homo sapiens (Human) |
| Expression Host | Human Cells |
| Tag Info | His or DYKDDDDK. Please contact us if you need further information or require specific designed tag. |
| Purity | Greater than 90% by SDS-PAGE gel |
| Uniprot ID | Q9Y224 |
| Entry Name | RTRAF_HUMAN |
| Gene Names | RTRAF C14orf166 CGI-99 |
| Alternative Gene Names | C14orf166 |
| Alternative Protein Names | RNA transcription, translation and transport factor protein (CLE7 homolog) (CLE) (hCLE) |
| Application | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only! |
| Buffer | Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives |
| Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
| Length | 244 |
| Molecular Weight(Da) | 28068 |
| Protein Sequence | (The sequence of expressed protein may have some variation from the sequence shown below. Please contact us for the exact sequence.) MFRRKLTALDYHNPAGFNCKDETEFRNFIVWLEDQKIRHYKIEDRGNLRNIHSSDWPKFFEKYLRDVNCPFKIQDRQEAIDWLLGLAVRLEYGDNAEKYKDLVPDNSKTADNATKNAEPLINLDVNNPDFKAGVMALANLLQIQRHDDYLVMLKAIRILVQERLTQDAVAKANQTKEGLPVALDKHILGFDTGDAVLNEAAQILRLLHIEELRELQTKINEAIVAVQAIIADPKTDHRLGKVGR |
Background
| Function | FUNCTION: RNA-binding protein involved in modulation of mRNA transcription by Polymerase II (PubMed:16950395). Component of the tRNA-splicing ligase complex and is required for tRNA ligation (PubMed:24870230). May be required for RNA transport (PubMed:24608264). {ECO:0000269|PubMed:16950395, ECO:0000269|PubMed:24608264, ECO:0000269|PubMed:24870230}.; FUNCTION: (Microbial infection) In case of infection by influenza virus A (IVA), is involved in viral replication (PubMed:21900157). {ECO:0000269|PubMed:21900157}. |
| Pathway | |
| Protein Families | RTRAF family |
| Tissue Specificity | Widely expressed. Expressed at high level in heart and skeletal muscle. Expressed at intermediate level in liver, pancreas, fetal brain and fetal lung. Weakly expressed in adult brain, adult lung, placenta, fetal liver and fetal kidney. Overexpressed in many brain tumors. {ECO:0000269|PubMed:15147888}. |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |