Specification
| Description | Recombinant protein from the full-length sequence of Homo sapiens ripply transcriptional repressor 3 (RIPPLY3), transcript variant 1 (NM_018962). |
| Organism | Homo sapiens (Human) |
| Expression Host | Human Cells |
| Tag Info | His or DYKDDDDK. Please contact us if you need further information or require specific designed tag. |
| Purity | Greater than 90% by SDS-PAGE gel |
| Uniprot ID | P57055 |
| Entry Name | DSCR6_HUMAN |
| Gene Names | RIPPLY3 DSCR6 |
| Alternative Gene Names | DSCR6 |
| Alternative Protein Names | Protein ripply3 (Down syndrome critical region protein 6) |
| Application | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only! |
| Buffer | Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives |
| Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
| Length | 190 |
| Molecular Weight(Da) | 20368 |
| Protein Sequence | (The sequence of expressed protein may have some variation from the sequence shown below. Please contact us for the exact sequence.) MEPEAAAGARKARGRGCHCPGDAPWRPPPPRGPESPAPWRPWIQTPGDAELTRTGRPLEPRADQHTFGSKGAFGFQHPVRVYLPMSKRQEYLRSSGEQVLASFPVQATIDFYDDESTESASEAEEPEEGPPPLHLLPQEVGGRQENGPGGKGRDQGINQGQRSSGGGDHWGEGPLPQGVSSRGGKCSSSK |
Background
| Function | FUNCTION: Acts as a transcriptional corepressor. Negative regulator of the transcriptional activity of TBX1. Plays a role in the development of the pharyngeal apparatus and derivatives (By similarity). {ECO:0000250}. |
| Pathway | |
| Protein Families | Ripply family |
| Tissue Specificity | Expressed at a low level in fetal kidney and fetal brain. {ECO:0000269|PubMed:10814524}. |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |