Specification
| Description | Recombinant protein from the full-length sequence of Homo sapiens ras homolog family member J (RHOJ) (NM_020663). |
| Organism | Homo sapiens (Human) |
| Expression Host | Human Cells |
| Tag Info | His or DYKDDDDK. Please contact us if you need further information or require specific designed tag. |
| Purity | Greater than 90% by SDS-PAGE gel |
| Uniprot ID | Q9H4E5 |
| Entry Name | RHOJ_HUMAN |
| Gene Names | RHOJ ARHJ RASL7B RHOI TCL |
| Alternative Gene Names | ARHJ RASL7B RHOI TCL |
| Alternative Protein Names | Rho-related GTP-binding protein RhoJ (Ras-like protein family member 7B) (Tc10-like GTP-binding protein) |
| Application | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only! |
| Buffer | Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives |
| Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
| Length | 214 |
| Molecular Weight(Da) | 23821 |
| Protein Sequence | (The sequence of expressed protein may have some variation from the sequence shown below. Please contact us for the exact sequence.) MNCKEGTDSSCGCRGNDEKKMLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVTVTVGGKQHLLGLYDTAGQEDYNQLRPLSYPNTDVFLICFSVVNPASYHNVQEEWVPELKDCMPHVPYVLIGTQIDLRDDPKTLARLLYMKEKPLTYEHGVKLAKAIGAQCYLECSALTQKGLKAVFDEAILTIFHPKKKKKRCSEGHSCCSII |
Background
| Function | FUNCTION: Plasma membrane-associated small GTPase specifically involved in angiogenesis (PubMed:21628409, PubMed:24434213, PubMed:30158707). Required for endothelial cell migration during vascular development via its interaction with GLUL (PubMed:30158707). Elicits the formation of F-actin-rich structures, thereby regulating endothelial cell migration (PubMed:30158707). {ECO:0000269|PubMed:21628409, ECO:0000269|PubMed:24434213, ECO:0000269|PubMed:30158707}. |
| Pathway | |
| Protein Families | Small GTPase superfamily, Rho family |
| Tissue Specificity | Specifically expressed in endothelial cells in different tissues, such as brain, heart, lung and liver. {ECO:0000269|PubMed:21628409}. |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |