Specification
| Description | Recombinant protein from the full-length sequence of Homo sapiens regulator of hemoglobinization and erythroid cell expansion (RHEX), transcript variant 1 (NM_001007544). |
| Organism | Homo sapiens (Human) |
| Expression Host | Human Cells |
| Tag Info | His or DYKDDDDK. Please contact us if you need further information or require specific designed tag. |
| Purity | Greater than 90% by SDS-PAGE gel |
| Uniprot ID | Q6ZWK4 |
| Entry Name | RHEX_HUMAN |
| Gene Names | RHEX C1orf186 |
| Alternative Gene Names | C1orf186 |
| Alternative Protein Names | Regulator of hemoglobinization and erythroid cell expansion protein (Regulator of human erythroid cell expansion protein) |
| Application | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only! |
| Buffer | Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives |
| Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
| Length | 172 |
| Molecular Weight(Da) | 19405 |
| Protein Sequence | (The sequence of expressed protein may have some variation from the sequence shown below. Please contact us for the exact sequence.) MLTEVMEVWHGLVIAVVSLFLQACFLTAINYLLSRHMAHKSEQILKAASLQVPRPSPGHHHPPAVKEMKETQTERDIPMSDSLYRHDSDTPSDSLDSSCSSPPACQATEDVDYTQVVFSDPGELKNDSPLDYENIKEITDYVNVNPERHKPSFWYFVNPALSEPAEYDQVAM |
Background
| Function | FUNCTION: Acts as a signaling transduction factor of the EPO-EPOR signaling pathway promoting erythroid cell differentiation (PubMed:25092874). {ECO:0000269|PubMed:25092874}. |
| Pathway | |
| Protein Families | |
| Tissue Specificity | Expressed in the proerythroblasts (at protein level) (PubMed:25092874). Expressed strongly in the kidney (PubMed:25092874). Expressed weakly in the pancreas, liver and lung (PubMed:25092874). Expressed strongly in erythroid progenitor cells (EPCs) (PubMed:25092874). Expressed weakly in T-cells and neutrophils (PubMed:25092874). {ECO:0000269|PubMed:25092874}. |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |