Specification
| Description | Recombinant protein from the full-length sequence of Homo sapiens retinol dehydrogenase 10 (RDH10) (NM_172037). |
| Organism | Homo sapiens (Human) |
| Expression Host | Human Cells |
| Tag Info | His or DYKDDDDK. Please contact us if you need further information or require specific designed tag. |
| Purity | Greater than 90% by SDS-PAGE gel |
| Uniprot ID | Q8IZV5 |
| Entry Name | RDH10_HUMAN |
| Gene Names | RDH10 SDR16C4 UNQ9375/PRO34191 |
| Alternative Gene Names | SDR16C4 |
| Alternative Protein Names | Retinol dehydrogenase 10 (EC 1.1.1.300) (Short chain dehydrogenase/reductase family 16C member 4) |
| Application | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only! |
| Buffer | Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives |
| Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
| Length | 341 |
| Molecular Weight(Da) | 38087 |
| Protein Sequence | (The sequence of expressed protein may have some variation from the sequence shown below. Please contact us for the exact sequence.) MNIVVEFFVVTFKVLWAFVLAAARWLVRPKEKSVAGQVCLITGAGSGLGRLFALEFARRRALLVLWDINTQSNEETAGMVRHIYRDLEAADAAALQAGNGEEEILPHCNLQVFTYTCDVGKRENVYLTAERVRKEVGEVSVLVNNAGVVSGHHLLECPDELIERTMMVNCHAHFWTTKAFLPTMLEINHGHIVTVASSLGLFSTAGVEDYCASKFGVVGFHESLSHELKAAEKDGIKTTLVCPYLVDTGMFRGCRIRKEIEPFLPPLKPDYCVKQAMKAILTDQPMICTPRLMYIVTFMKSILPFEAVVCMYRFLGADKCMYPFIAQRKQATNNNEAKNGI |
Background
| Function | FUNCTION: Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinol to all-trans-retinal. Has no detectable activity towards 11-cis-retinol, 9-cis-retinol and 13-cis-retinol. {ECO:0000269|PubMed:12407145}. |
| Pathway | Cofactor metabolism; retinol metabolism. |
| Protein Families | Short-chain dehydrogenases/reductases (SDR) family |
| Tissue Specificity | Detected in retina, kidney, liver, small intestine, placenta, lung, heart and skeletal muscle. {ECO:0000269|PubMed:12407145, ECO:0000269|PubMed:14596915}. |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |