Specification
| Description | Recombinant protein from the full-length sequence of Homo sapiens RAP2B, member of RAS oncogene family (RAP2B) (NM_002886). |
| Organism | Homo sapiens (Human) |
| Expression Host | Human Cells |
| Tag Info | His or DYKDDDDK. Please contact us if you need further information or require specific designed tag. |
| Purity | Greater than 90% by SDS-PAGE gel |
| Uniprot ID | P61225 |
| Entry Name | RAP2B_HUMAN |
| Gene Names | RAP2B |
| Alternative Gene Names | |
| Alternative Protein Names | Ras-related protein Rap-2b (EC 3.6.5.2) |
| Application | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only! |
| Buffer | Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives |
| Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
| Length | 183 |
| Molecular Weight(Da) | 20504 |
| Protein Sequence | (The sequence of expressed protein may have some variation from the sequence shown below. Please contact us for the exact sequence.) MREYKVVVLGSGGVGKSALTVQFVTGSFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYERVPMILVGNKVDLEGEREVSYGEGKALAEEWSCPFMETSAKNKASVDELFAEIVRQMNYAAQPNGDEGCCSACVIL |
Background
| Function | FUNCTION: Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. Involved in EGFR and CHRM3 signaling pathways through stimulation of PLCE1. May play a role in cytoskeletal rearrangements and regulate cell spreading through activation of the effector TNIK. May regulate membrane vesiculation in red blood cells. {ECO:0000269|PubMed:11877431, ECO:0000269|PubMed:15143162, ECO:0000269|PubMed:16540189}. |
| Pathway | |
| Protein Families | Small GTPase superfamily, Ras family |
| Tissue Specificity | Expressed in red blood cells (at protein level). {ECO:0000269|PubMed:16540189}. |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |