Specification
| Organism | Homo sapiens (Human) |
| Expression Host | E.coli |
| Tag Info | N-terminal 6xHis-SUMO-tagged |
| Purity | Greater than 85% by SDS-PAGE |
| Uniprot ID | Q9UNQ2 |
| Gene Names | DIMT1 |
| Alternative Names | DIM1 dimethyladenosine transferase 1 homologDIM1 dimethyladenosine transferase 1-likeProbable 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferaseProbable 18S rRNA dimethylaseProbable S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase |
| Expression Region | Full Length(1-313aa ) |
| Molecular Weight | 51.2 kDa |
| Protein Sequence | MPKVKSGAIGRRRGRQEQRRELKSAGGLMFNTGIGQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVASKLQVLVGDVLKTDLPFFDTCVANLPYQISSPFVFKLLLHRPFFRCAILMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKNNFRPPPKVESSVVRIEPKNPPPPINFQEWDGLVRITFVRKNKTLSAAFKSSAVQQLLEKNYRIHCSVHNIIIPEDFSIADKIQQILTSTGFSDKRARSMDIDDFIRLLHGFNAEGIHFS |
| Form | Liquid or Lyophilization |
| Buffer | The default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol if the delivery form is liquid. The lyophilization buffer is Tris/PBS-based buffer, 6% Trehalose, pH 8.0 if the delivery form is lyophilized powder. Please contact us if you have any special requirment. |
| Reconstitution | Please reconstitute protein in deionized sterile water and we recommend that briefly centrifuge thevial prior to opening the vial .We recommend aliquot for long-term storage at -20℃/-80℃. |
Background
| Relevance | Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle. |
| Involvement in Disease | |
| Subcellular Location | Nucleus, nucleoplasm, Nucleus, nucleolus |
| Protein Families | Class I-like SAM-binding methyltransferase superfamily, rRNA adenine N(6)-methyltransferase family |
| Tissue Specificity | DIMT1 |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |