Specification
| Description | Recombinant protein from the full-length sequence of Homo sapiens ORMDL sphingolipid biosynthesis regulator 2 (ORMDL2) (NM_014182). |
| Organism | Homo sapiens (Human) |
| Expression Host | Human Cells |
| Tag Info | His or DYKDDDDK. Please contact us if you need further information or require specific designed tag. |
| Purity | Greater than 90% by SDS-PAGE gel |
| Uniprot ID | Q53FV1 |
| Entry Name | ORML2_HUMAN |
| Gene Names | ORMDL2 HSPC160 MSTP095 |
| Alternative Gene Names | |
| Alternative Protein Names | ORM1-like protein 2 (Adoplin-2) |
| Application | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only! |
| Buffer | Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives |
| Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
| Length | 153 |
| Molecular Weight(Da) | 17363 |
| Protein Sequence | (The sequence of expressed protein may have some variation from the sequence shown below. Please contact us for the exact sequence.) MNVGVAHSEVNPNTRVMNSRGIWLAYIILVGLLHMVLLSIPFFSIPVVWTLTNVIHNLATYVFLHTVKGTPFETPDQGKARLLTHWEQMDYGLQFTSSRKFLSISPIVLYLLASFYTKYDAAHFLINTASLLSVLLPKLPQFHGVRVFGINKY |
Background
| Function | FUNCTION: Negative regulator of sphingolipid synthesis. {ECO:0000269|PubMed:20182505}. |
| Pathway | |
| Protein Families | ORM family |
| Tissue Specificity | Widely expressed. Expressed in adult and fetal heart, brain, lung, liver, skeletal muscle and kidney. Expressed in adult pancreas and placenta and in fetal spleen abd thymus. {ECO:0000269|PubMed:12093374}. |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |