Specification
| Organism | Homo sapiens (Human) |
| Expression Host | Yeast |
| Tag Info | N-terminal 6xHis-tagged |
| Purity | Greater than 85% by SDS-PAGE |
| Uniprot ID | P08246 |
| Gene Names | ELANE |
| Alternative Names | Bone marrow serine protease;Elastase-2Human leukocyte elastase ;HLEMedullasin;PMN elastase |
| Expression Region | Full Length of Mature Protein(30-267aa ) |
| Molecular Weight | 27.6 kDa |
| Protein Sequence | IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNLSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSLCRRSNVCTLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRSEDNPCPHPRDPDPASRTH |
| Form | Liquid or Lyophilization |
| Buffer | The default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol if the delivery form is liquid. The lyophilization buffer is Tris/PBS-based buffer, 6% Trehalose, pH 8.0 if the delivery form is lyophilized powder. Please contact us if you have any special requirment. |
| Reconstitution | Please reconstitute protein in deionized sterile water and we recommend that briefly centrifuge thevial prior to opening the vial .We recommend aliquot for long-term storage at -20℃/-80℃. |
Background
| Relevance | Modifies the functions of natural killer cells, monocytes and granulocytes. Inhibits C5a-dependent neutrophil enzyme release and chotaxis. |
| Involvement in Disease | Cyclic haematopoiesis (CH); Neutropenia, severe congenital 1, autosomal dominant (SCN1) |
| Subcellular Location | |
| Protein Families | Peptidase S1 family, Elastase subfamily |
| Tissue Specificity | ELANE |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |