Specification
| Organism | Homo sapiens (Human) |
| Expression Host | E.coli |
| Tag Info | N-terminal GST-tagged |
| Purity | Greater than 85% by SDS-PAGE |
| Uniprot ID | P16860 |
| Gene Names | NPPB |
| Alternative Names | Gamma-brain natriuretic peptide |
| Expression Region | Partial(37-71aa ) |
| Molecular Weight | 31 kDa |
| Protein Sequence | DLETSGLQEQRNHLQGKLSELQVEQTSLEPLQESP |
| Form | Liquid or Lyophilization |
| Buffer | The default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol if the delivery form is liquid. The lyophilization buffer is Tris/PBS-based buffer, 6% Trehalose, pH 8.0 if the delivery form is lyophilized powder. Please contact us if you have any special requirment. |
| Reconstitution | Please reconstitute protein in deionized sterile water and we recommend that briefly centrifuge thevial prior to opening the vial .We recommend aliquot for long-term storage at -20℃/-80℃. |
Background
| Relevance | Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3. |
| Involvement in Disease | |
| Subcellular Location | Secreted |
| Protein Families | Natriuretic peptide family |
| Tissue Specificity | NPPB |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |