Specification
| Description | Recombinant protein from the full-length sequence of Homo sapiens keratin associated protein 3-3 (KRTAP3-3) (NM_033185). |
| Organism | Homo sapiens (Human) |
| Expression Host | Human Cells |
| Tag Info | His or DYKDDDDK. Please contact us if you need further information or require specific designed tag. |
| Purity | Greater than 90% by SDS-PAGE gel |
| Uniprot ID | Q9BYR6 |
| Entry Name | KRA33_HUMAN |
| Gene Names | KRTAP3-3 KAP3.3 KRTAP3.3 |
| Alternative Gene Names | KAP3.3 KRTAP3.3 |
| Alternative Protein Names | Keratin-associated protein 3-3 (High sulfur keratin-associated protein 3.3) (Keratin-associated protein 3.3) |
| Application | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only! |
| Buffer | Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives |
| Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
| Length | 98 |
| Molecular Weight(Da) | 10365 |
| Protein Sequence | (The sequence of expressed protein may have some variation from the sequence shown below. Please contact us for the exact sequence.) MDCCASRGCSVPTGPATTICSSDKSCRCGVCLPSTCPHTVWLLEPTCCDNCPPPCHIPQPCVPTCFLLNSCQPTPGLETLNLTTFTQPCCEPCLPRGC |
Background
| Function | FUNCTION: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins. |
| Pathway | |
| Protein Families | KRTAP type 3 family |
| Tissue Specificity | Localized to the upper cortex of the hair shaft. {ECO:0000269|PubMed:11279113}. |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |