Specification
| Organism | Homo sapiens (Human) |
| Expression Host | E.Coli |
| Tag Info | Tag-Free |
| Purity | >98% as determined by SDS-PAGE and HPLC. |
| Uniprot ID | P05112 |
| Uniprot Entry Name | IL4_HUMAN |
| Gene Names | IL4 |
| Alternative Names | IL-4, BSF-1, Binetrakin, Lymphocyte stimulatory factor 1, Pitrakinra |
| Expression Region | Full Length of Mature Protein (25-153aa) |
| Molecular Weight | 15.0 kDa |
| Endotoxin | Less than 1.0 EU/µg as determined by LAL method. |
| Sequence | HKCDITLQEI IKTLNSLTEQ KTLCTELTVT DIFAASKNTT EKETFCRAAT VLRQFYSHHE KDTRCLGATA QQFHRHKQLI RFLKRLDRNL WGLAGLNSCP VKEANQSTLE NFLERLKTIM REKYSKCSS |
| Product Form | Lyophilized powder (Lyophilized from a 0.2 µm filtered PBS, pH 7.4) |
| Reconstitution | Please reconstitute protein in deionized sterile water and we recommend that briefly centrifuge thevial prior to opening the vial .We recommend aliquot for long-term storage at -20℃/-80℃. |
Background
| Relevance | Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. |
| Function | Participates in at least several B-cell activation processes as well as of other cell types |
| Involvement in disease | Ischemic stroke (ISCHSTR) |
| Subcellular Location | Secreted |
| Protein Families | IL-4/IL-13 family |
| Tissue Specificity | |
| Pathway | Jak-STATsignalingpathway |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |