Specification
| Organism | Homo sapiens (Human) |
| Expression Host | E.Coli |
| Tag Info | Tag-Free |
| Purity | >95% as determined by SDS-PAGE and HPLC. |
| Uniprot ID | Q96PD4 |
| Uniprot Entry Name | IL17F_HUMAN |
| Gene Names | IL17F |
| Alternative Names | IL-17F, |
| Expression Region | Full Length of Mature Protein (31-163aa) |
| Molecular Weight | 15 kDa |
| Endotoxin | Less than 1.0 EU/µg as determined by LAL method. |
| Sequence | M+RKIPKVGHT FFQKPESCPP VPGGSMKLDI GIINENQRVS MSRNIESRST SPWNYTVTWD PNRYPSEVVQ AQCRNLGCIN AQGKEDISMN SVPIQQETLV VRRKHQGCSV SFQLEKVLVT VGCTCVTPVI HHVQ |
| Product Form | Lyophilized powder (Lyophilized from a 0.2 µm filtered PBS, pH 7.4) |
| Reconstitution | Please reconstitute protein in deionized sterile water and we recommend that briefly centrifuge thevial prior to opening the vial .We recommend aliquot for long-term storage at -20℃/-80℃. |
Background
| Relevance | Stimulates the production of other cytokines such as IL-6, IL-8 and granulocyte colony-stimulating factor, and can regulate cartilage matrix turnover. Stimulates PBMC and T-cell proliferation. Inhibits angiogenesis. |
| Function | Ligand for IL17RA and IL17RC |
| Involvement in disease | Candidiasis, familial, 6 (CANDF6) |
| Subcellular Location | Secreted |
| Protein Families | IL-17 family |
| Tissue Specificity | Expressed in activated, but not resting, CD4+ T-cells and activated monocytes. |
| Pathway | IL-17signalingpathway |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |