Specification
| Organism | Homo sapiens (Human) |
| Expression Host | E.Coli |
| Tag Info | Tag-Free |
| Purity | >95% as determined by SDS-PAGE and HPLC. |
| Uniprot ID | Q16552 |
| Uniprot Entry Name | IL17_HUMAN |
| Gene Names | IL17A,CTLA8,IL17 |
| Alternative Names | IL-17, Cytotoxic T-lymphocyte-associated antigen 8, CTLA-8 |
| Expression Region | Full Length of Mature Protein (24-155aa) |
| Molecular Weight | 15.1 kDa |
| Endotoxin | Less than 1.0 EU/µg as determined by LAL method. |
| Sequence | GITIPRNPGC PNSEDKNFPR TVMVNLNIHN RNTNTNPKRS SDYYNRSTSP WNLHRNEDPE RYPSVIWEAK CRHLGCINAD GNVDYHMNSV PIQQEILVLR REPPHCPNSF RLEKILVSVG CTCVTPIVHH VA |
| Product Form | Lyophilized powder (Lyophilized from a 0.2 µm filtered PBS, pH 7.4) |
| Reconstitution | Please reconstitute protein in deionized sterile water and we recommend that briefly centrifuge thevial prior to opening the vial .We recommend aliquot for long-term storage at -20℃/-80℃. |
Background
| Relevance | Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts. |
| Function | Ligand for IL17RA and IL17RC |
| Involvement in disease | |
| Subcellular Location | Secreted |
| Protein Families | IL-17 family |
| Tissue Specificity | Restricted to activated memory T-cells. |
| Pathway | IL-17signalingpathway |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |