Specification
| Organism | Homo sapiens (Human) |
| Expression Host | E.Coli |
| Tag Info | Tag-Free |
| Purity | >98% as determined by SDS-PAGE and HPLC. |
| Uniprot ID | P01579 |
| Uniprot Entry Name | IFNG_HUMAN |
| Gene Names | IFNG |
| Alternative Names | IFN-gamma, |
| Expression Region | Full Length of Mature Protein (M+24-166aa) |
| Molecular Weight | 16.9 kDa |
| Endotoxin | Less than 1.0 EU/µg as determined by LAL method. |
| Sequence | MQDPYVKEAE NLKKYFNAGH SDVADNGTLF LGILKNWKEE SDRKIMQSQI VSFYFKLFKN FKDDQSIQKS VETIKEDMNV KFFNSNKKKR DDFEKLTNYS VTDLNVQRKA IHELIQVMAE LSPAAKTGKR KRSQMLFRGR RASQ |
| Product Form | Lyophilized powder (Lyophilized from a 0.2 µm filtered PBS, pH 7.4) |
| Reconstitution | Please reconstitute protein in deionized sterile water and we recommend that briefly centrifuge thevial prior to opening the vial .We recommend aliquot for long-term storage at -20℃/-80℃. |
Background
| Relevance | Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. |
| Function | Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. |
| Involvement in disease | Aplastic anemia (AA) |
| Subcellular Location | Secreted |
| Protein Families | Type II (or gamma) interferon family |
| Tissue Specificity | Released primarily from activated T lymphocytes. |
| Pathway | HIF-1signalingpathway |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |