Specification
| Organism | Homo sapiens (Human) |
| Expression Host | E.coli |
| Tag Info | N-terminal GST-tagged |
| Purity | Greater than 85% by SDS-PAGE |
| Uniprot ID | O95251 |
| Gene Names | KAT7 |
| Alternative Names | Histone acetyltransferase binding to OR;C1Lysine acetyltransferase 7MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2 ;MYST-2 |
| Expression Region | Partial(1-214aa ) |
| Molecular Weight | 50.8 kDa |
| Protein Sequence | MPRRKRNAGSSSDGTEDSDFSTDLEHTDSSESDGTSRRSARVTRSSARLSQSSQDSSPVRNLQSFGTEEPAYSTRRVTRSQQQPTPVTPKKYPLRQTRSSGSETEQVVDFSDRETKNTADHDESPPRTPTGNAPSSESDIDISSPNVSHDESIAKDMSLKDSGSDLSHRPKRRRFHESYNFNMKCPTPGCNSLGHLTGKHERHFSISGCPLYHN |
| Form | Liquid or Lyophilization |
| Buffer | The default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol if the delivery form is liquid. The lyophilization buffer is Tris/PBS-based buffer, 6% Trehalose, pH 8.0 if the delivery form is lyophilized powder. Please contact us if you have any special requirment. |
| Reconstitution | Please reconstitute protein in deionized sterile water and we recommend that briefly centrifuge thevial prior to opening the vial .We recommend aliquot for long-term storage at -20℃/-80℃. |
Background
| Relevance | Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may regulate DNA replication and act as a coactivator of TP53-dependent transcription. Specifically represses AR-mediated transcription. |
| Involvement in Disease | |
| Subcellular Location | Nucleus, nucleoplasm, Cytoplasm, cytosol, Nucleus |
| Protein Families | MYST (SAS/MOZ) family |
| Tissue Specificity | KAT7 |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |