Specification
| Description | Recombinant protein from the full-length sequence of Homo sapiens guanylate cyclase activator 1C (GUCA1C), transcript variant 1 (NM_005459). |
| Organism | Homo sapiens (Human) |
| Expression Host | Human Cells |
| Tag Info | His or DYKDDDDK. Please contact us if you need further information or require specific designed tag. |
| Purity | Greater than 90% by SDS-PAGE gel |
| Uniprot ID | O95843 |
| Entry Name | GUC1C_HUMAN |
| Gene Names | GUCA1C GCAP3 |
| Alternative Gene Names | GCAP3 |
| Alternative Protein Names | Guanylyl cyclase-activating protein 3 (GCAP 3) (Guanylate cyclase activator 1C) |
| Application | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only! |
| Buffer | Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives |
| Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
| Length | 209 |
| Molecular Weight(Da) | 23822 |
| Protein Sequence | (The sequence of expressed protein may have some variation from the sequence shown below. Please contact us for the exact sequence.) MGNGKSIAGDQKAVPTQETHVWYRTFMMEYPSGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGMAKDQDLLEIVYKSFDFSNVLRVICNGKQPDMETDSSKSPDKAGLGKVKMK |
Background
| Function | FUNCTION: Stimulates guanylyl cyclase 1 (GC1) and GC2 when free calcium ions concentration is low and inhibits guanylyl cyclases when free calcium ions concentration is elevated. This Ca(2+)-sensitive regulation of guanylyl cyclase (GC) is a key event in recovery of the dark state of rod photoreceptors following light exposure. |
| Pathway | |
| Protein Families | |
| Tissue Specificity | Retina. |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |