Specification
| Organism | Homo sapiens (Human) |
| Expression Host | E.coli |
| Tag Info | N-terminal 6xHis-SUMO-tagged |
| Purity | Greater than 85% by SDS-PAGE |
| Uniprot ID | Q8NFF5 |
| Gene Names | FLAD1 |
| Alternative Names | FAD pyrophosphorylaseFMN adenylyltransferaseFlavin adenine dinucleotide synthase 2 domains:Molybdenum cofactor biosynthesis protein-like regionFAD synthase region |
| Expression Region | Full Length of Isoform 2(1-490aa ) |
| Molecular Weight | 70.2 kDa |
| Protein Sequence | MTSRASELSPGRSVTAGIIIVGDEILKGHTQDTNTFFLCRTLRSLGVQVCRVSVVPDEVATIAAEVTSFSNRFTHVLTAGGIGPTHDDVTFEAVAQAFGDELKPHPKLEAATKALGGEGWEKLSLVPSSARLHYGTDPCTGQPFRFPLVSVRNVYLFPGIPELLRRVLEGMKGLFQNPAVQFHSKELYVAADEASIAPILAEAQAHFGRRLGLGSYPDWGSNYYQVKLTLDSEEEGPLEECLAYLTARLPQGSLVPYMPNAVEQASEAVYKLAESGSSLGKKVAGALQTIETSLAQYSLTQLCVGFNGGKDCTALLHLFHAAVQRKLPDVPNPLQILYIRSISPFPELEQFLQDTIKRYNLQMLEAEGSMKQALGELQARHPQLEAVLMGTRRTDPYSCSLCPFSPTDPGWPAFMRINPLLDWTYRDIWDFLRQLFVPYCILYDRGYTSLGSRENTVRNPALKCLSPGGHPTYRPAYLLENEEEERNSRT |
| Form | Liquid or Lyophilization |
| Buffer | The default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol if the delivery form is liquid. The lyophilization buffer is Tris/PBS-based buffer, 6% Trehalose, pH 8.0 if the delivery form is lyophilized powder. Please contact us if you have any special requirment. |
| Reconstitution | Please reconstitute protein in deionized sterile water and we recommend that briefly centrifuge thevial prior to opening the vial .We recommend aliquot for long-term storage at -20℃/-80℃. |
Background
| Relevance | Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme. |
| Involvement in Disease | Lipid storage myopathy due to flavin adenine dinucleotide synthetase deficiency (LSMFLAD) |
| Subcellular Location | Isoform 1: Mitochondrion matrix, SUBCELLULAR LOCATION: Isoform 2: Cytoplasm |
| Protein Families | MoaB/Mog family; PAPS reductase family, FAD1 subfamily |
| Tissue Specificity | FLAD1 |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |