Specification
| Organism | Homo sapiens (Human) |
| Expression Host | E.Coli |
| Tag Info | Tag-Free |
| Purity | >97% as determined by SDS-PAGE and HPLC. |
| Uniprot ID | P51671 |
| Uniprot Entry Name | CCL11_HUMAN |
| Gene Names | CCL11,SCYA11 |
| Alternative Names | C-C motif chemokine 11, Small-inducible cytokine A11 |
| Expression Region | Full Length of Mature Protein (24-97aa) |
| Molecular Weight | 8.4 kDa |
| Endotoxin | Less than 1.0 EU/µg as determined by LAL method. |
| Sequence | GPASVPTTCC FNLANRKIPL QRLESYRRIT SGKCPQKAVI FKTKLAKDICADPKKKWVQD SMKYLDQKSP TPKP |
| Product Form | Lyophilized powder (Lyophilized from a 0.2 μm filtered 20 mM PB, pH 7.4, 150 mM NaCl) |
| Reconstitution | Please reconstitute protein in deionized sterile water and we recommend that briefly centrifuge thevial prior to opening the vial .We recommend aliquot for long-term storage at -20℃/-80℃. |
Background
| Relevance | In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3. |
| Function | In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3. |
| Involvement in disease | |
| Subcellular Location | Secreted |
| Protein Families | Intercrine beta (chemokine CC) family |
| Tissue Specificity | |
| Pathway | Chemokinesignalingpathway |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |