Specification
| Description | Recombinant protein from the full-length sequence of Homo sapiens destrin, actin depolymerizing factor (DSTN), transcript variant 1 (NM_006870). |
| Organism | Homo sapiens (Human) |
| Expression Host | Human Cells |
| Tag Info | His or DYKDDDDK. Please contact us if you need further information or require specific designed tag. |
| Purity | Greater than 90% by SDS-PAGE gel |
| Uniprot ID | P60981 |
| Entry Name | DEST_HUMAN |
| Gene Names | DSTN ACTDP DSN |
| Alternative Gene Names | ACTDP DSN |
| Alternative Protein Names | Destrin (Actin-depolymerizing factor) (ADF) |
| Application | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only! |
| Buffer | Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives |
| Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
| Length | 165 |
| Molecular Weight(Da) | 18506 |
| Protein Sequence | (The sequence of expressed protein may have some variation from the sequence shown below. Please contact us for the exact sequence.) MASGVQVADEVCRIFYDMKVRKCSTPEEIKKRKKAVIFCLSADKKCIIVEEGKEILVGDVGVTITDPFKHFVGMLPEKDCRYALYDASFETKESRKEELMFFLWAPELAPLKSKMIYASSKDAIKKKFQGIKHECQANGPEDLNRACIAEKLGGSLIVAFEGCPV |
Background
| Function | FUNCTION: Actin-depolymerizing protein. Severs actin filaments (F-actin) and binds to actin monomers (G-actin). Acts in a pH-independent manner. {ECO:0000269|PubMed:11812157}. |
| Pathway | |
| Protein Families | Actin-binding proteins ADF family |
| Tissue Specificity | Widely distributed in various tissues. |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |