Specification
| Description | Recombinant protein from the full-length sequence of Homo sapiens DnaJ heat shock protein family (Hsp40) member C8 (DNAJC8), transcript variant 1 (NM_014280). |
| Organism | Homo sapiens (Human) |
| Expression Host | Human Cells |
| Tag Info | His or DYKDDDDK. Please contact us if you need further information or require specific designed tag. |
| Purity | Greater than 90% by SDS-PAGE gel |
| Uniprot ID | O75937 |
| Entry Name | DNJC8_HUMAN |
| Gene Names | DNAJC8 SPF31 HSPC315 HSPC331 |
| Alternative Gene Names | SPF31 |
| Alternative Protein Names | DnaJ homolog subfamily C member 8 (Splicing protein spf31) |
| Application | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only! |
| Buffer | Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives |
| Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
| Length | 253 |
| Molecular Weight(Da) | 29842 |
| Protein Sequence | (The sequence of expressed protein may have some variation from the sequence shown below. Please contact us for the exact sequence.) MAASGESGTSGGGGSTEEAFMTFYSEVKQIEKRDSVLTSKNQIERLTRPGSSYFNLNPFEVLQIDPEVTDEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQKKRALDVIQAGKEYVEHTVKERKKQLKKEGKPTIVEEDDPELFKQAVYKQTMKLFAELEIKRKEREAKEMHERKRQREEEIEAQEKAKREREWQKNFEESRDGRVDSWRNFQANTKGKKEKKNRTFLRPPKVKMEQRE |
Background
| Function | FUNCTION: Suppresses polyglutamine (polyQ) aggregation of ATXN3 in neuronal cells (PubMed:27133716). {ECO:0000269|PubMed:27133716}. |
| Pathway | |
| Protein Families | |
| Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:27133716}. |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |