Specification
| Organism | Homo sapiens (Human) |
| Expression Host | E.coli |
| Tag Info | N-terminal GST-tagged |
| Purity | Greater than 85% by SDS-PAGE |
| Uniprot ID | P20674 |
| Gene Names | COX5A |
| Alternative Names | Cytochrome c oxidase polypeptide Va |
| Expression Region | Full Length of Mature Protein(42-150aa ) |
| Molecular Weight | 39.5 kDa |
| Protein Sequence | SHGSQETDEEFDARWVTYFNKPDIDAWELRKGINTLVTYDMVPEPKIIDAALRACRRLNDFASTVRILEVVKDKAGPHKEIYPYVIQELRPTLNELGISTPEELGLDKV |
| Form | Liquid or Lyophilization |
| Buffer | The default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol if the delivery form is liquid. The lyophilization buffer is Tris/PBS-based buffer, 6% Trehalose, pH 8.0 if the delivery form is lyophilized powder. Please contact us if you have any special requirment. |
| Reconstitution | Please reconstitute protein in deionized sterile water and we recommend that briefly centrifuge thevial prior to opening the vial .We recommend aliquot for long-term storage at -20℃/-80℃. |
Background
| Relevance | This is the he A-containing chain of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. |
| Involvement in Disease | Mitochondrial complex IV deficiency is a rare condition caused by mutation in COX5A that lead to pulmonary arterial hypertension (PAH), failure to thrive and lactic acidemia. |
| Subcellular Location | Mitochondrion inner membrane |
| Protein Families | Cytochrome c oxidase subunit 5A family |
| Tissue Specificity | COX5A |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |