Specification
| Description | Recombinant protein from the full-length sequence of Homo sapiens cytochrome c oxidase assembly factor 8 (COA8), transcript variant 1, mRNA (NM_001370595). |
| Organism | Homo sapiens (Human) |
| Expression Host | Human Cells |
| Tag Info | His or DYKDDDDK. Please contact us if you need further information or require specific designed tag. |
| Purity | Greater than 90% by SDS-PAGE gel |
| Uniprot ID | Q96IL0 |
| Entry Name | COA8_HUMAN |
| Gene Names | COA8 APOP1 APOPT1 C14orf153 |
| Alternative Gene Names | APOP1 APOPT1 C14orf153 |
| Alternative Protein Names | Cytochrome c oxidase assembly factor 8 (COA8) (Apoptogenic protein 1, mitochondrial) (APOP-1) |
| Application | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only! |
| Buffer | Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives |
| Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
| Length | 206 |
| Molecular Weight(Da) | 24153 |
| Protein Sequence | (The sequence of expressed protein may have some variation from the sequence shown below. Please contact us for the exact sequence.) MLPCAAGARGRGAMVVLRAGKKTFLPPLCRAFACRGCQLAPERGAERRDTAPSGVSRFCPPRKSCHDWIGPPDKYSNLRPVHFYIPENESPLEQKLRKLRQETQEWNQQFWANQNLTFSKEKEEFIHSRLKTKGLGLRTESGQKATLNAEEMADFYKEFLSKNFQKHMYYNRDWYKRNFAITFFMGKVALERIWNKLKQKQKKRSN |
Background
| Function | FUNCTION: Required for cytochrome c complex (COX) IV assembly and function Protects COX assembly from oxidation-induced degradation, COX being the terminal component of the mitochondrial respiratory chain. {ECO:0000269|PubMed:25175347, ECO:0000269|PubMed:30552096}. |
| Pathway | |
| Protein Families | COA8 family |
| Tissue Specificity | Expressed in fibroblasts. {ECO:0000269|PubMed:25175347}. |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |