Specification
| Description | Recombinant protein from the full-length sequence of homo sapiens C-type lectin domain family 12 member B (CLEC12B), transcript variant 1 (NM_001129998). |
| Organism | Homo sapiens (Human) |
| Expression Host | Human Cells |
| Tag Info | His or DYKDDDDK. Please contact us if you need further information or require specific designed tag. |
| Purity | Greater than 90% by SDS-PAGE gel |
| Uniprot ID | Q2HXU8 |
| Entry Name | CL12B_HUMAN |
| Gene Names | CLEC12B UNQ5782/PRO16089 |
| Alternative Gene Names | |
| Alternative Protein Names | C-type lectin domain family 12 member B (Macrophage antigen H) |
| Application | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only! |
| Buffer | Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives |
| Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
| Length | 276 |
| Molecular Weight(Da) | 31616 |
| Protein Sequence | (The sequence of expressed protein may have some variation from the sequence shown below. Please contact us for the exact sequence.) MSEEVTYATLTFQDSAGARNNRDGNNLRKRGHPAPSPIWRHAALGLVTLCLMLLIGLVTLGMMFLQISNDINSDSEKLSQLQKTIQQQQDNLSQQLGNSNNLSMEEEFLKSQISSVLKRQEQMAIKLCQELIIHTSDHRCNPCPKMWQWYQNSCYYFTTNEEKTWANSRKDCIDKNSTLVKIDSLEEKDFLMSQPLLMFSFFWLGLSWDSSGRSWFWEDGSVPSPSLFSTKELDQINGSKGCAYFQKGNIYISRCSAEIFWICEKTAAPVKTEDLD |
Background
| Function | FUNCTION: Cell surface receptor that protects target cells against natural killer cell-mediated lysis. Modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases. {ECO:0000269|PubMed:17562706}. |
| Pathway | |
| Protein Families | |
| Tissue Specificity | Detected in colon, heart, kidney, liver, lung, mammary gland, ovary, spleen and testis. {ECO:0000269|PubMed:17562706}. |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |