Specification
| Organism | Homo sapiens (Human) |
| Expression Host | E.coli |
| Tag Info | N-terminal 6xHis-SUMO-tagged |
| Purity | Greater than 85% by SDS-PAGE |
| Uniprot ID | Q5SYC1 |
| Gene Names | CLVS2 |
| Alternative Names | Retinaldehyde-binding protein 1-like 2 |
| Expression Region | Full Length(1-327aa ) |
| Molecular Weight | 54 kDa |
| Protein Sequence | MTHLQAGLSPETLEKARLELNENPDTLHQDIQEVRDMVITRPDIGFLRTDDAFILRFLRARKFHHFEAFRLLAQYFEYRQQNLDMFKSFKATDPGIKQALKDGFPGGLANLDHYGRKILVLFAANWDQSRYTLVDILRAILLSLEAMIEDPELQVNGFVLIIDWSNFTFKQASKLTPSMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFLKEKTRKRIFLHGNNLNSLHQLIHPEILPSEFGGMLPPYDMGTWARTLLDHEYDDDSEYNVDSYSMPVKEVEKELSPKSMKRSQSVVDPTVLKRMDKNEEENMQPLLSLD |
| Form | Liquid or Lyophilization |
| Buffer | The default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol if the delivery form is liquid. The lyophilization buffer is Tris/PBS-based buffer, 6% Trehalose, pH 8.0 if the delivery form is lyophilized powder. Please contact us if you have any special requirment. |
| Reconstitution | Please reconstitute protein in deionized sterile water and we recommend that briefly centrifuge thevial prior to opening the vial .We recommend aliquot for long-term storage at -20℃/-80℃. |
Background
| Relevance | Required for normal morphology of late endosomes and/or lysosomes in neurons . Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).1 Publication |
| Involvement in Disease | |
| Subcellular Location | Golgi apparatus, trans-Golgi network membrane, Peripheral membrane protein, Cytoplasmic vesicle, clathrin-coated vesicle, Early endosome membrane, Peripheral membrane protein |
| Protein Families | |
| Tissue Specificity | CLVS2 |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |