Specification
| Description | Recombinant protein from the full-length sequence of Homo sapiens cyclin dependent kinase inhibitor 2C (CDKN2C), transcript variant 1 (NM_001262). |
| Organism | Homo sapiens (Human) |
| Expression Host | Human Cells |
| Tag Info | His or DYKDDDDK. Please contact us if you need further information or require specific designed tag. |
| Purity | Greater than 90% by SDS-PAGE gel |
| Uniprot ID | P42773 |
| Entry Name | CDN2C_HUMAN |
| Gene Names | CDKN2C CDKN6 |
| Alternative Gene Names | CDKN6 |
| Alternative Protein Names | Cyclin-dependent kinase 4 inhibitor C (Cyclin-dependent kinase 6 inhibitor) (p18-INK4c) (p18-INK6) |
| Application | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only! |
| Buffer | Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives |
| Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
| Length | 168 |
| Molecular Weight(Da) | 18127 |
| Protein Sequence | (The sequence of expressed protein may have some variation from the sequence shown below. Please contact us for the exact sequence.) MAEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAGGATNLQ |
Background
| Function | FUNCTION: Interacts strongly with CDK6, weakly with CDK4. Inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB. |
| Pathway | |
| Protein Families | CDKN2 cyclin-dependent kinase inhibitor family |
| Tissue Specificity | Highest levels found in skeletal muscle. Also found in pancreas and heart. |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |