Specification
| Description | Recombinant protein from the full-length sequence of Homo sapiens C1q and TNF related 4 (C1QTNF4) (NM_031909). |
| Organism | Homo sapiens (Human) |
| Expression Host | Human Cells |
| Tag Info | His or DYKDDDDK. Please contact us if you need further information or require specific designed tag. |
| Purity | Greater than 90% by SDS-PAGE gel |
| Uniprot ID | Q9BXJ3 |
| Entry Name | C1QT4_HUMAN |
| Gene Names | C1QTNF4 CTRP4 |
| Alternative Gene Names | CTRP4 |
| Alternative Protein Names | Complement C1q tumor necrosis factor-related protein 4 (C1q/TNF-related protein 4) |
| Application | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only! |
| Buffer | Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives |
| Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
| Length | 329 |
| Molecular Weight(Da) | 35256 |
| Protein Sequence | (The sequence of expressed protein may have some variation from the sequence shown below. Please contact us for the exact sequence.) MLPLLLGLLGPAACWALGPTPGPGSSELRSAFSAARTTPLEGTSEMAVTFDKVYVNIGGDFDVATGQFRCRVPGAYFFSFTAGKAPHKSLSVMLVRNRDEVQALAFDEQRRPGARRAASQSAMLQLDYGDTVWLRLHGAPQYALGAPGATFSGYLVYADADADAPARGPPAPPEPRSAFSAARTRSLVGSDAGPGPRHQPLAFDTEFVNIGGDFDAAAGVFRCRLPGAYFFSFTLGKLPRKTLSVKLMKNRDEVQAMIYDDGASRRREMQSQSVMLALRRGDAVWLLSHDHDGYGAYSNHGKYITFSGFLVYPDLAPAAPPGLGASELL |
Background
| Function | FUNCTION: May be involved in the regulation of the inflammatory network. Its role as pro- or anti-inflammatory seems to be context dependent (PubMed:21658842, PubMed:27086950). Seems to have some role in regulating food intake and energy balance when administered in the brain. This effect is sustained over a two-day period, and it is accompanied by decreased expression of orexigenic neuropeptides in the hypothalamus 3 hours post-injection (By similarity). {ECO:0000250|UniProtKB:Q8R066, ECO:0000269|PubMed:21658842, ECO:0000269|PubMed:27086950}. |
| Pathway | |
| Protein Families | |
| Tissue Specificity | Widely expressed at low levels (PubMed:21658842). Highest levels in adipocyte tissue and brain (PubMed:24366864). {ECO:0000269|PubMed:21658842, ECO:0000269|PubMed:24366864}. |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |