Specification
| Organism | Homo sapiens (Human) |
| Expression Host | E.Coli |
| Tag Info | Tag-Free |
| Purity | >97% as determined by SDS-PAGE and HPLC. |
| Uniprot ID | O00175 |
| Uniprot Entry Name | CCL24_HUMAN |
| Gene Names | CCL24,MPIF2,SCYA24 |
| Alternative Names | CK-beta-6, Eotaxin-2, Myeloid progenitor inhibitory factor 2, MPIF-2, Small-inducible cytokine A24 |
| Expression Region | Partial (27-104aa) |
| Molecular Weight | 8.8 kDa |
| Endotoxin | Less than 1.0 EU/µg as determined by LAL method. |
| Sequence | VVIPSPCCMF FVSKRIPENR VVSYQLSSRS TCLKAGVIFT TKKGQQFCGD PKQEWVQRYM KNLDAKQKKA SPRARAVA |
| Product Form | Lyophilized powder (Lyophilized from a 0.2 µm filtered PBS, pH 7.4) |
| Reconstitution | Please reconstitute protein in deionized sterile water and we recommend that briefly centrifuge thevial prior to opening the vial .We recommend aliquot for long-term storage at -20℃/-80℃. |
Background
| Relevance | Chemotactic for resting T-lymphocytes, and eosinophils. Has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. Is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. Binds to CCR3. |
| Function | Chemotactic for resting T-lymphocytes, and eosinophils. Has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. Is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. Binds to CCR3. |
| Involvement in disease | |
| Subcellular Location | Secreted |
| Protein Families | Intercrine beta (chemokine CC) family |
| Tissue Specificity | Activated monocytes and activated T lymphocytes. |
| Pathway | Chemokinesignalingpathway |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |