Specification
| Organism | Homo sapiens (Human) |
| Expression Host | E.Coli |
| Tag Info | Tag-Free |
| Purity | >97% as determined by SDS-PAGE and HPLC. |
| Uniprot ID | Q92583 |
| Uniprot Entry Name | CCL17_HUMAN |
| Gene Names | CCL17,SCYA17,TARC |
| Alternative Names | CC chemokine TARC, Thymus and activation-regulated chemokine |
| Expression Region | Full Length of Mature Protein (24-94aa) |
| Molecular Weight | 8.1 kDa |
| Endotoxin | Less than 1.0 EU/µg as determined by LAL method. |
| Sequence | ARGTNVGREC CLEYFKGAIP LRKLKTWYQT SEDCSRDAIV FVTVQGRAIC SDPNNKRVKN AVKYLQSLER S |
| Product Form | Lyophilized powder (Lyophilized from a 0.2 μm filtered 20mM PB, pH 7.4, 150mM NaCl) |
| Reconstitution | Please reconstitute protein in deionized sterile water and we recommend that briefly centrifuge thevial prior to opening the vial .We recommend aliquot for long-term storage at -20℃/-80℃. |
Background
| Relevance | Chemotactic factor for T-lymphocytes but not monocytes or granulocytes. May play a role in T-cell development in thymus and in trafficking and activation of mature T-cells. Binds to CCR4. {ECO:0000269|PubMed:10540332}. |
| Function | Chemotactic factor for T-lymphocytes but not monocytes or granulocytes. May play a role in T-cell development in thymus and in trafficking and activation of mature T-cells. Binds to CCR4. |
| Involvement in disease | |
| Subcellular Location | Secreted |
| Protein Families | Intercrine beta (chemokine CC) family |
| Tissue Specificity | Expressed at high levels in thymus and at low levels in the lung, colon and small intestine. |
| Pathway | Chemokinesignalingpathway |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |