Specification
| Description | Recombinant protein from the full-length sequence of Homo sapiens BLOC-1 related complex subunit 5 (BORCS5), transcript variant 1 (NM_058169). |
| Organism | Homo sapiens (Human) |
| Expression Host | Human Cells |
| Tag Info | His or DYKDDDDK. Please contact us if you need further information or require specific designed tag. |
| Purity | Greater than 90% by SDS-PAGE gel |
| Uniprot ID | Q969J3 |
| Entry Name | BORC5_HUMAN |
| Gene Names | BORCS5 LOH12CR1 |
| Alternative Gene Names | LOH12CR1 |
| Alternative Protein Names | BLOC-1-related complex subunit 5 (Loss of heterozygosity 12 chromosomal region 1) (Myristoylated lysosomal protein) (Myrlysin) |
| Application | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only! |
| Buffer | Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives |
| Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
| Length | 196 |
| Molecular Weight(Da) | 22222 |
| Protein Sequence | (The sequence of expressed protein may have some variation from the sequence shown below. Please contact us for the exact sequence.) MGSEQSSEAESRPNDLNSSVTPSPAKHRAKMDDIVVVAQGSQASRNVSNDPDVIKLQEIPTFQPLLKGLLSGQTSPTNAKLEKLDSQQVLQLCLRYQDHLHQCAEAVAFDQNALVKRIKEMDLSVETLFSFMQERQKRYAKYAEQIQKVNEMSAILRRIQMGIDQTVPLLDRLNSMLPEGERLEPFSMKPDRELRL |
Background
| Function | FUNCTION: As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor. Thereby, it may indirectly play a role in cell spreading and motility. {ECO:0000269|PubMed:25898167}. |
| Pathway | |
| Protein Families | BORCS5 family |
| Tissue Specificity | Ubiquitously expressed (at protein level). {ECO:0000269|PubMed:11896457, ECO:0000269|PubMed:25898167}. |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |