Specification
| Organism | Homo sapiens (Human) |
| Expression Host | E.Coli |
| Tag Info | Tag-Free |
| Purity | >98% as determined by SDS-PAGE and HPLC. |
| Uniprot ID | Q8WTQ1 |
| Uniprot Entry Name | D104A_HUMAN |
| Gene Names | DEFB104A,DEFB104,DEFB4;,DEFB104B |
| Alternative Names | Beta-defensin 4, DEFB-4, hBD-4, Defensin, beta 104, |
| Expression Region | Full Length of Mature Protein (23-72aa) |
| Molecular Weight | 6.0 kDa |
| Endotoxin | Less than 1.0 EU/µg as determined by LAL method. |
| Sequence | EFELDRICGY GTARCRKKCR SQEYRIGRCP NTYACCLRKW DESLLNRTKP |
| Product Form | Lyophilized powder (Lyophilized from a 0.2 µm filtered 20 mM PB, pH 7.4, 130 mM NaCl) |
| Reconstitution | Please reconstitute protein in deionized sterile water and we recommend that briefly centrifuge thevial prior to opening the vial .We recommend aliquot for long-term storage at -20℃/-80℃. |
Background
| Relevance | Has antimicrobial activity. Synergistic effects with lysozyme and DEFB103. {ECO:0000269|PubMed:11481241}. |
| Function | Has antimicrobial activity. Synergistic effects with lysozyme and DEFB103. |
| Involvement in disease | |
| Subcellular Location | Secreted |
| Protein Families | Beta-defensin family |
| Tissue Specificity | High expression in the testis. Gastric antrum exhibited relatively high levels. A lower expression is observed in uterus and neutrophils thyroid gland, lung, and kidney. No detectable expression in other tissues tested. |
| Pathway |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |